Hereditary breast and ovarian cancer syndrome is a type of familial cancer, and is linked to mutations in
two genes called BRCA1 and BRCA2. BRCA1 and BRCA2 are known as tumour suppressor genes – they
prevent cells from growing too rapidly or in an uncontrolled way. Thousands of mutations have been
found in these genes, but only some have been linked to an increased risk of cancer.

Lipoprotein (a) also referred to as Lp (a) is structurally similar to LDL- C with the exception of the presence of apolipoprotein (a) or apo (a) moiety attached to its apo B component1. Apo(a) shares homology with the fibrin binding domain of plasminogen leading to impaired conversion to its active form plasmin. 

D-dimer has been in use for almost three decades, as a screening tool for Venous thromboembolism (VTE)¹. It is one of many Fibrin degradation products (FDP) produced after a clot is degraded by the process of fibrinolysis. FDPs come in a variety of molecular weights.